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A Minimal PKPD Interaction Model for Evaluating Synergy Effects of Combined NSCLC Therapies

This paper introduces a mathematical compartmental formulation of dose-effect synergy modelling for multiple therapies in non small cell lung cancer (NSCLC): antiangiogenic, immuno- and radiotherapy. The model formulates the dose-effect relationship in a unified context, with tumor proliferating rat...

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Detalles Bibliográficos
Autores principales: Ionescu, Clara Mihaela, Ghita, Maria, Copot, Dana, Derom, Eric, Verellen, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356515/
https://www.ncbi.nlm.nih.gov/pubmed/32545464
http://dx.doi.org/10.3390/jcm9061832