Heparin Blocks the Inhibition of Tissue Kallikrein 1 by Kallistatin through Electrostatic Repulsion

Kallistatin, also known as SERPINA4, has been implicated in the regulation of blood pressure and angiogenesis, due to its specific inhibition of tissue kallikrein 1 (KLK1) and/or by its heparin binding ability. The binding of heparin on kallistatin has been shown to block the inhibition of KLK1 by k...

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Detalles Bibliográficos
Autores principales: Ma, Lina, Wu, Jiawei, Zheng, Ying, Shu, Zimei, Wei, Zhenquan, Sun, Yinbiao, Carrell, Robin W., Zhou, Aiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356578/
https://www.ncbi.nlm.nih.gov/pubmed/32481593
http://dx.doi.org/10.3390/biom10060828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356578/
https://www.ncbi.nlm.nih.gov/pubmed/32481593
http://dx.doi.org/10.3390/biom10060828

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