Computer-Aided Discovery of New Solubility-Enhancing Drug Delivery System

The poor aqueous solubility of active pharmaceutical ingredients (APIs) places a limit on their therapeutic potential. Cyclodextrins (CDs) have been shown to improve the solubility of APIs, but the magnitude of the improvement depends on the structure of both the CDs and APIs. We have developed quan...

Descripción completa

Detalles Bibliográficos
Autores principales: Mizera, Mikołaj, Muratov, Eugene N., Alves, Vinicius M., Tropsha, Alexander, Cielecka-Piontek, Judyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356584/
https://www.ncbi.nlm.nih.gov/pubmed/32560246
http://dx.doi.org/10.3390/biom10060913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356584/
https://www.ncbi.nlm.nih.gov/pubmed/32560246
http://dx.doi.org/10.3390/biom10060913

Ejemplares similares