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Hydrogel Formulations Incorporating Drug Nanocrystals Enhance the Therapeutic Effect of Rebamipide in a Hamster Model for Oral Mucositis

A mouthwash formulation of rebamipide (REB) is commonly used to treat oral mucositis; however, this formulation does not provide sufficient treatment or prevention in cases of serious oral mucositis. To improve treatment, we attempted to design a hydrogel incorporating REB nanocrystals (R-NPs gel)....

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Seiriki, Ryotaro, Deguchi, Saori, Otake, Hiroko, Hiramatsu, Noriko, Sasaki, Hiroshi, Yamamoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356607/
https://www.ncbi.nlm.nih.gov/pubmed/32527029
http://dx.doi.org/10.3390/pharmaceutics12060532