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Tumor Immune Microenvironment Clusters in Localized Prostate Adenocarcinoma: Prognostic Impact of Macrophage Enriched/Plasma Cell Non-Enriched Subtypes

Background: Prostate cancer (PCa) is characterized by significant heterogeneity in its molecular, genomic, and immunologic characteristics. Methods: Whole transcriptome RNAseq data from The Cancer Genome Atlas of prostate adenocarcinomas (n = 492) was utilized. The immune microenvironment was charac...

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Detalles Bibliográficos
Autores principales: Jairath, Neil K., Farha, Mark W., Srinivasan, Sudharsan, Jairath, Ruple, Green, Michael D., Dess, Robert T., Jackson, William C., Weiner, Adam B., Schaeffer, Edward M., Zhao, Shuang G., Feng, Felix Y., El Naqa, Issam, Spratt, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356642/
https://www.ncbi.nlm.nih.gov/pubmed/32599760
http://dx.doi.org/10.3390/jcm9061973