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Impact of Insoluble Separation Layer Mechanical Properties on Disintegration and Dissolution Kinetics of Multilayer Tablets

Dissolution and disintegration of solid dosage forms such as multiple-layer tablet with different active ingredients depend on formulation and properties used in the formulations, and it may sometimes result in counterintuitive release kinetics. In this manuscript, we investigate the behavior of com...

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Detalles Bibliográficos
Autores principales: Yokoyama, Reiji, Kimura, Go, Huwyler, Jörg, Hosoya, Ken-ichi, Puchkov, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356680/
https://www.ncbi.nlm.nih.gov/pubmed/32485803
http://dx.doi.org/10.3390/pharmaceutics12060495