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Synthesis and Antimicrobial Studies of Coumarin-Substituted Pyrazole Derivatives as Potent Anti-Staphylococcus aureus Agents

In this paper, synthesis and antimicrobial studies of 31 novel coumarin-substituted pyrazole derivatives are reported. Some of these compounds have shown potent activity against methicillin-resistant Staphylococcus aureus (MRSA) with minimum inhibitory concentration (MIC) as low as 3.125 µg/mL. Thes...

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Detalles Bibliográficos
Autores principales: Alnufaie, Rawan, Raj KC, Hansa, Alsup, Nickolas, Whitt, Jedidiah, Andrew Chambers, Steven, Gilmore, David, Alam, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356691/
https://www.ncbi.nlm.nih.gov/pubmed/32549248
http://dx.doi.org/10.3390/molecules25122758