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The Role of Cocrystallization-Mediated Altered Crystallographic Properties on the Tabletability of Rivaroxaban and Malonic Acid

The present work aims to understand the crystallographic basis of the mechanical behavior of rivaroxaban-malonic acid cocrystal (RIV-MAL Co) in comparison to its parent constituents, i.e., rivaroxaban (RIV) and malonic acid (MAL). The mechanical behavior was evaluated at the bulk level by performing...

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Detalles Bibliográficos
Autores principales: Kale, Dnyaneshwar P., Puri, Vibha, Kumar, Amit, Kumar, Navin, Bansal, Arvind K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356764/
https://www.ncbi.nlm.nih.gov/pubmed/32545503
http://dx.doi.org/10.3390/pharmaceutics12060546