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Structure-Activity Relationships for the Anaesthetic and Analgaesic Properties of Aromatic Ring-Substituted Ketamine Esters

A series of benzene ring substituted ketamine N-alkyl esters were prepared from the corresponding substituted norketamines. Few of the latter have been reported since they have not been generally accessible via known routes. We report a new general route to many of these norketamines via the Neber (...

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Detalles Bibliográficos
Autores principales: Dimitrov, Ivaylo V., Harvey, Martyn G., Voss, Logan J., Sleigh, James W., Bickerdike, Michael J., Denny, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356787/
https://www.ncbi.nlm.nih.gov/pubmed/32604891
http://dx.doi.org/10.3390/molecules25122950