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Photodegradation of the H(1) Antihistaminic Topical Drugs Emedastine, Epinastine, and Ketotifen and ROS Tests for Estimations of Their Potent Phototoxicity

In this study, important H(1) antihistaminic drugs, i.e., emedastine (EME), epinastine (EPI), and ketotifen (KET), were irradiated with UV/Vis light (300–800 nm) in solutions of different pH values. Next, they were analyzed by new high performance liquid chromatography (HPLC) methods, in order to es...

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Detalles Bibliográficos
Autores principales: Gumieniczek, Anna, Berecka-Rycerz, Anna, Hubicka, Urszula, Żmudzki, Paweł, Lejwoda, Karolina, Kozyra, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356818/
https://www.ncbi.nlm.nih.gov/pubmed/32560381
http://dx.doi.org/10.3390/pharmaceutics12060560