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Development of an HPLC-MS/MS Method for the Determination of Silybin in Human Plasma, Urine and Breast Tissue

Silybin is a flavonolignan extracted from Silybum marianum with chemopreventive activity against various cancers, including breast. This study was designed to develop an HPLC-MS/MS method for the determination of silybin in human plasma, urine and breast tissue in early breast cancer patients underg...

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Detalles Bibliográficos
Autores principales: Lazzeroni, Matteo, Petrangolini, Giovanna, Legarreta Iriberri, José Antonio, Pascual Avellana, Jaume, Tost Robusté, Digna, Cagnacci, Sara, Macis, Debora, Aristarco, Valentina, Bonanni, Bernardo, Morazzoni, Paolo, Johansson, Harriet, Riva, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356828/
https://www.ncbi.nlm.nih.gov/pubmed/32599946
http://dx.doi.org/10.3390/molecules25122918