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Subtilisin-Involved Morphology Engineering for Improved Antibiotic Production in Actinomycetes

In the submerged cultivation of filamentous microbes, including actinomycetes, complex morphology is one of the critical process features for the production of secondary metabolites. Ansamitocin P-3 (AP-3), an antitumor agent, is a secondary metabolite produced by Actinosynnema pretiosum ATCC 31280....

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Detalles Bibliográficos
Autores principales: Wu, Yuanting, Kang, Qianjin, Zhang, Li-Li, Bai, Linquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356834/
https://www.ncbi.nlm.nih.gov/pubmed/32503302
http://dx.doi.org/10.3390/biom10060851