Molecular Image-Based Prediction Models of Nuclear Receptor Agonists and Antagonists Using the DeepSnap-Deep Learning Approach with the Tox21 10K Library

The interaction of nuclear receptors (NRs) with chemical compounds can cause dysregulation of endocrine signaling pathways, leading to adverse health outcomes due to the disruption of natural hormones. Thus, identifying possible ligands of NRs is a crucial task for understanding the adverse outcome...

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Detalles Bibliográficos
Autores principales: Matsuzaka, Yasunari, Uesawa, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356846/
https://www.ncbi.nlm.nih.gov/pubmed/32549344
http://dx.doi.org/10.3390/molecules25122764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356846/
https://www.ncbi.nlm.nih.gov/pubmed/32549344
http://dx.doi.org/10.3390/molecules25122764

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