Immunoadsorption for Treatment of Patients with Suspected Alzheimer Dementia and Agonistic Autoantibodies against Alpha1a-Adrenoceptor—Rationale and Design of the IMAD Pilot Study

Background: agonistic autoantibodies (agAABs) against G protein-coupled receptors (GPCR) have been linked to cardiovascular disease. In dementia patients, GPCR-agAABs against the α1- and ß2-adrenoceptors (α1AR- and ß2AR) were found at a prevalence of 50%. Elimination of agAABs by immunoadsorption (I...

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Detalles Bibliográficos
Autores principales: Stracke, Sylvia, Lange, Sandra, Bornmann, Sarah, Kock, Holger, Schulze, Lara, Klinger-König, Johanna, Böhm, Susanne, Vogelgesang, Antje, von Podewils, Felix, Föel, Agnes, Gross, Stefan, Wenzel, Katrin, Wallukat, Gerd, Prüss, Harald, Dressel, Alexander, Kunze, Rudolf, Grabe, Hans J., Langner, Sönke, Dörr, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356934/
https://www.ncbi.nlm.nih.gov/pubmed/32575439
http://dx.doi.org/10.3390/jcm9061919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356934/
https://www.ncbi.nlm.nih.gov/pubmed/32575439
http://dx.doi.org/10.3390/jcm9061919

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