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Comparison between Colistin Sulfate Dry Powder and Solution for Pulmonary Delivery

To assess the difference in the fate of the antibiotic colistin (COLI) after its pulmonary delivery as a powder or a solution, we developed a COLI powder and evaluated the COLI pharmacokinetic properties in rats after pulmonary administration of the powder or the solution. The amorphous COLI powder...

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Detalles Bibliográficos
Autores principales: Tewes, Frédéric, Brillault, Julien, Gregoire, Nicolas, Olivier, Jean-Christophe, Lamarche, Isabelle, Adier, Christophe, Healy, Anne-Marie, Marchand, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356940/
https://www.ncbi.nlm.nih.gov/pubmed/32560289
http://dx.doi.org/10.3390/pharmaceutics12060557