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Intrinsic Dissolution Rate Profiling of Poorly Water-Soluble Compounds in Biorelevant Dissolution Media

The intrinsic dissolution rate (IDR) of active pharmaceutical ingredients (API) is a key property that aids in early drug development, especially selecting formulation strategies to improve dissolution and thereby drug absorption in the intestine. Here, we developed a robust method for rapid, medium...

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Detalles Bibliográficos
Autores principales: Teleki, Alexandra, Nylander, Olivia, Bergström, Christel A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356998/
https://www.ncbi.nlm.nih.gov/pubmed/32481718
http://dx.doi.org/10.3390/pharmaceutics12060493