Drug Release from a Spherical Matrix: Theoretical Analysis for a Finite Dissolution Rate Affected by Geometric Shape of Dispersed Drugs

Amending the neglect of finite dissolution in traditional release models, this study proposed a more generalized drug release model considering the simultaneous dissolution and diffusion procedure from a drug-loaded spherical matrix. How the shape factor (n = 0, 1/2, and 2/3 for the planar, cylindri...

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Detalles Bibliográficos
Autores principales: Lin, Yung-Sheng, Tsay, Ruey-Yug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357057/
https://www.ncbi.nlm.nih.gov/pubmed/32585967
http://dx.doi.org/10.3390/pharmaceutics12060582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357057/
https://www.ncbi.nlm.nih.gov/pubmed/32585967
http://dx.doi.org/10.3390/pharmaceutics12060582

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