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The Performance of Gene Expression Signature-Guided Drug–Disease Association in Different Categories of Drugs and Diseases

A gene expression signature (GES) is a group of genes that shows a unique expression profile as a result of perturbations by drugs, genetic modification or diseases on the transcriptional machinery. The comparisons between GES profiles have been used to investigate the relationships between drugs, t...

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Detalles Bibliográficos
Autores principales: Qi, Xiguang, Shen, Mingzhe, Fan, Peihao, Guo, Xiaojiang, Wang, Tianqi, Feng, Ning, Zhang, Manling, Sweet, Robert A., Kirisci, Levent, Wang, Lirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357095/
https://www.ncbi.nlm.nih.gov/pubmed/32560162
http://dx.doi.org/10.3390/molecules25122776