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Development and Evaluation of Docetaxel-Phospholipid Complex Loaded Self-Microemulsifying Drug Delivery System: Optimization and In Vitro/Ex Vivo Studies

Docetaxel (DTX) has clinical efficacy in the treatment of breast cancer, but it is difficult to develop a product for oral administration, due to low solubility and permeability. This study focused on preparing a self-microemulsifying drug delivery system (SME) loaded with DTX-phospholipid complex (...

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Detalles Bibliográficos
Autores principales: Wang, Miao, You, Sung-Kyun, Lee, Hong-Ki, Han, Min-Gu, Lee, Hyeon-Min, Pham, Thi Mai Anh, Na, Young-Guk, Cho, Cheong-Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357111/
https://www.ncbi.nlm.nih.gov/pubmed/32545452
http://dx.doi.org/10.3390/pharmaceutics12060544