Bioanalytical Method Development and Validation of Veratraldehyde and Its Metabolite Veratric Acid in Rat Plasma: An Application for a Pharmacokinetic Study

A simple, sensitive, and rapid UHPLC-MS/MS method was developed for the simultaneous determination of veratraldehyde and its metabolite veratric acid in rat plasma. Cinnamaldehyde was used as an internal standard (IS) and the one-step protein precipitation method with 0.2% formic acid in acetonitril...

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Detalles Bibliográficos
Autores principales: Huh, Hyun Wook, Song, Hee-Yong, Na, Young-Guk, Kim, Minki, Han, Mingu, Pham, Thi Mai Anh, Lee, Hyeonmin, Suh, Jungkyu, Lee, Seok-Jong, Lee, Hong-Ki, Cho, Cheong-Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357115/
https://www.ncbi.nlm.nih.gov/pubmed/32560470
http://dx.doi.org/10.3390/molecules25122800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357115/
https://www.ncbi.nlm.nih.gov/pubmed/32560470
http://dx.doi.org/10.3390/molecules25122800

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