Cargando…

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions

The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress; however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis (TLS) over damaged nucleotides is a major source of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodriguez-Alvarez, Marta, Kim, Daria, Khobta, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357151/
https://www.ncbi.nlm.nih.gov/pubmed/32545792
http://dx.doi.org/10.3390/biom10060902