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EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions
The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress; however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis (TLS) over damaged nucleotides is a major source of p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357151/ https://www.ncbi.nlm.nih.gov/pubmed/32545792 http://dx.doi.org/10.3390/biom10060902 |