The Effect of Calcium Buffering and Calcium Sensor Type on the Sensitivity of an Array-Based Bitter Receptor Screening Assay

The genetically encoded calcium sensor protein Cameleon YC3.6 has previously been applied for functional G protein–coupled receptor screening using receptor cell arrays. However, different types of sensors are available, with a wide range in [Ca(2+)] sensitivity, Hill coefficients, calcium binding d...

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Detalles Bibliográficos
Autores principales: Roelse, Margriet, Wehrens, Ron, Henquet, Maurice Gl, Witkamp, Renger F, Hall, Robert D, Jongsma, Maarten A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357244/
https://www.ncbi.nlm.nih.gov/pubmed/31278864
http://dx.doi.org/10.1093/chemse/bjz044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357244/
https://www.ncbi.nlm.nih.gov/pubmed/31278864
http://dx.doi.org/10.1093/chemse/bjz044

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