Pooled CRISPR screens with imaging on microRaft arrays reveals stress granule-regulatory factors

Genetic screens using pooled CRISPR-based approaches are scalable and inexpensive, but restricted to standard readouts including survival, proliferation and sortable markers. However, many biologically relevant cell states involve cellular and subcellular changes that are only accessible by microsco...

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Detalles Bibliográficos
Autores principales: Wheeler, Emily C., Vu, Anthony Q., Einstein, Jaclyn M., DiSalvo, Matthew, Ahmed, Noorsher, Van Nostrand, Eric L., Shishkin, Alexander A., Jin, Wenhao, Allbritton, Nancy L., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357298/
https://www.ncbi.nlm.nih.gov/pubmed/32393832
http://dx.doi.org/10.1038/s41592-020-0826-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357298/
https://www.ncbi.nlm.nih.gov/pubmed/32393832
http://dx.doi.org/10.1038/s41592-020-0826-8

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