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APOE ϵ4 modifies the relationship between infectious burden and poor cognition

OBJECTIVE: We investigated whether APOE ϵ4 is an effect modifier of the association between infectious burden (IB) and poor cognition in a multiethnic cohort, the Northern Manhattan Study. METHODS: IB was assessed by a quantitative weighted index of exposure to common pathogens associated with vascu...

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Detalles Bibliográficos
Autores principales: Zhao, Chen, Strobino, Kevin, Moon, Yeseon Park, Cheung, Ying Kuen, Sacco, Ralph L., Stern, Yaakov, Elkind, Mitchell S.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357411/
https://www.ncbi.nlm.nih.gov/pubmed/32754642
http://dx.doi.org/10.1212/NXG.0000000000000462