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Pseudopterosin and O-Methyltylophorinidine Suppress Cell Growth in a 3D Spheroid Co-Culture Model of Pancreatic Ductal Adenocarcinoma

Current therapies for treating pancreatic ductal adenocarcinoma (PDAC) are largely ineffective, with the desmoplastic environment established within these tumors being considered a central issue. We established a 3D spheroid co-culture in vitro model using a PDAC cell line (either PANC-1 or Capan-2)...

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Detalles Bibliográficos
Autores principales: Xie, Bailu, Hänsel, Jan, Mundorf, Vanessa, Betz, Janina, Reimche, Irene, Erkan, Mert, Büdeyri, Ibrahim, Gesell, Anne, Kerr, Russell G., Ariantari, Ni Putu, Yu, Haiqian, Proksch, Peter, Teusch, Nicole, Mrsny, Randall J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357459/
https://www.ncbi.nlm.nih.gov/pubmed/32545910
http://dx.doi.org/10.3390/bioengineering7020057