Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases

Ancestral sequence reconstruction and resurrection provides useful information for protein engineering, yet its alliance with directed evolution has been little explored. In this study, we have resurrected several ancestral nodes of fungal laccases dating back ∼500 to 250 million years. Unlike moder...

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Detalles Bibliográficos
Autores principales: Gomez-Fernandez, Bernardo J., Risso, Valeria A., Rueda, Andres, Sanchez-Ruiz, Jose M., Alcalde, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357490/
https://www.ncbi.nlm.nih.gov/pubmed/32414792
http://dx.doi.org/10.1128/AEM.00778-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357490/
https://www.ncbi.nlm.nih.gov/pubmed/32414792
http://dx.doi.org/10.1128/AEM.00778-20

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