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Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases
Ancestral sequence reconstruction and resurrection provides useful information for protein engineering, yet its alliance with directed evolution has been little explored. In this study, we have resurrected several ancestral nodes of fungal laccases dating back ∼500 to 250 million years. Unlike moder...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357490/ https://www.ncbi.nlm.nih.gov/pubmed/32414792 http://dx.doi.org/10.1128/AEM.00778-20 |