Antiviral immunity and nucleic acid sensing in haematopoietic stem cell gene engineering

The low gene manipulation efficiency of human hematopoietic stem and progenitor cells (HSPC) remains a major hurdle for sustainable and broad clinical application of innovative therapies for a wide range of disorders. Given that all current and emerging gene transfer and editing technologies are bou...

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Detalles Bibliográficos
Autores principales: Piras, Francesco, Kajaste-Rudnitski, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357672/
https://www.ncbi.nlm.nih.gov/pubmed/32661282
http://dx.doi.org/10.1038/s41434-020-0175-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357672/
https://www.ncbi.nlm.nih.gov/pubmed/32661282
http://dx.doi.org/10.1038/s41434-020-0175-3

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