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Antiviral immunity and nucleic acid sensing in haematopoietic stem cell gene engineering
The low gene manipulation efficiency of human hematopoietic stem and progenitor cells (HSPC) remains a major hurdle for sustainable and broad clinical application of innovative therapies for a wide range of disorders. Given that all current and emerging gene transfer and editing technologies are bou...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357672/ https://www.ncbi.nlm.nih.gov/pubmed/32661282 http://dx.doi.org/10.1038/s41434-020-0175-3 |