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An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions

Transcription factors are important regulators of cell fate and function. Knowledge about where transcription factors are bound in the genome is crucial for understanding their function. A common method to study protein-DNA interactions is chromatin immunoprecipitation (ChIP). Here, we present a rev...

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Detalles Bibliográficos
Autores principales: de Jonge, Wim J., Brok, Mariël, Kemmeren, Patrick, Holstege, Frank C.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357673/
https://www.ncbi.nlm.nih.gov/pubmed/32685929
http://dx.doi.org/10.1016/j.xpro.2020.100020