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Producing Soluble Human Programmed Cell Death Protein-1: A Natural Supporter for CD4+T Cell Cytotoxicity and Tumor Cells Apoptosis

BACKGROUND: Programmed cell death protein-1 (PD-1)/PD-L1 pathway is one of the immune checkpoint pathways involved in the regulation of the immune responses and the suppression of anti-tumor defense. PD-1/PD-L1 blocking antibodies improve immune responses such as cytotoxic activity of CD8(+)/CD4(+)T...

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Detalles Bibliográficos
Autores principales: Mohammadzadeh, Samane, Khanahmad, Hossein, Esmaeil, Nafiseh, Eskandari, Nahid, Rahimmanesh, Ilnaz, Rezaei, Abbas, Andalib, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357696/
https://www.ncbi.nlm.nih.gov/pubmed/32671122
http://dx.doi.org/10.30498/IJB.2019.85180