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Producing Soluble Human Programmed Cell Death Protein-1: A Natural Supporter for CD4+T Cell Cytotoxicity and Tumor Cells Apoptosis
BACKGROUND: Programmed cell death protein-1 (PD-1)/PD-L1 pathway is one of the immune checkpoint pathways involved in the regulation of the immune responses and the suppression of anti-tumor defense. PD-1/PD-L1 blocking antibodies improve immune responses such as cytotoxic activity of CD8(+)/CD4(+)T...
Autores principales: | Mohammadzadeh, Samane, Khanahmad, Hossein, Esmaeil, Nafiseh, Eskandari, Nahid, Rahimmanesh, Ilnaz, Rezaei, Abbas, Andalib, Alireza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Genetic Engineering and Biotechnology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357696/ https://www.ncbi.nlm.nih.gov/pubmed/32671122 http://dx.doi.org/10.30498/IJB.2019.85180 |
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