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Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genes cooperatively with Hmo1 in Saccharomyces cerevisiae

Fpr1 (FK506-sensitive proline rotamase 1), a protein of the FKBP12 (FK506-binding protein 12 kDa) family in Saccharomyces cerevisiae, is a primary target for the immunosuppressive agents FK506 and rapamycin. Fpr1 inhibits calcineurin and TORC1 (target of rapamycin complex 1) when bound to FK506 and...

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Detalles Bibliográficos
Autores principales: Kasahara, Koji, Nakayama, Risa, Shiwa, Yuh, Kanesaki, Yu, Ishige, Taichiro, Yoshikawa, Hirofumi, Kokubo, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357790/
https://www.ncbi.nlm.nih.gov/pubmed/32603360
http://dx.doi.org/10.1371/journal.pgen.1008865