Macromolecular Crowding Enhances the Detection of DNA and Proteins by a Solid-State Nanopore

[Image: see text] Nanopore analysis of nucleic acid is now routine, but detection of proteins remains challenging. Here, we report the systematic characterization of the effect of macromolecular crowding on the detection sensitivity of a solid-state nanopore for circular and linearized DNA plasmids,...

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Detalles Bibliográficos
Autores principales: Chau, Chalmers C., Radford, Sheena E., Hewitt, Eric W., Actis, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357865/
https://www.ncbi.nlm.nih.gov/pubmed/32559088
http://dx.doi.org/10.1021/acs.nanolett.0c02246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357865/
https://www.ncbi.nlm.nih.gov/pubmed/32559088
http://dx.doi.org/10.1021/acs.nanolett.0c02246

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