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一种新的CD123嵌合抗原受体T细胞的构建及其抗白血病作用探究

OBJECTIVE: To construct a new CD123-specific chimeric antigen receptor in order to provide a foundation for immunotherapy of CD123 positive leukemia. METHODS: A hybridoma strain(6E11)capable of stably secreting CD123 antibody was obtained by a monoclonal screening technique, and the hybridoma cells...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357918/
https://www.ncbi.nlm.nih.gov/pubmed/32311887
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2020.03.002