CD56 regulates human NK cell cytotoxicity through Pyk2

Human natural killer (NK) cells are defined as CD56(+)CD3(−). Despite its ubiquitous expression on human NK cells the role of CD56 (NCAM) in human NK cell cytotoxic function has not been defined. In non-immune cells, NCAM can induce signaling, mediate adhesion, and promote exocytosis through interac...

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Detalles Bibliográficos
Autores principales: Gunesch, Justin T, Dixon, Amera L, Ebrahim, Tasneem AM, Berrien-Elliott, Melissa M, Tatineni, Swetha, Kumar, Tejas, Hegewisch-Solloa, Everardo, Fehniger, Todd A, Mace, Emily M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358009/
https://www.ncbi.nlm.nih.gov/pubmed/32510326
http://dx.doi.org/10.7554/eLife.57346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358009/
https://www.ncbi.nlm.nih.gov/pubmed/32510326
http://dx.doi.org/10.7554/eLife.57346

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