Primary Resistance to Combination Therapy with First- and Third-Generation EGFR Tyrosine Kinase Inhibitors of Lung Adenocarcinoma Harboring EGFR 19Del/T790M/in Trans-C797S Mutations with Co-Occurring CTNNB1 Alteration

BACKGROUND: Epidermal growth factor receptor (EGFR) in trans-C797S alteration has been considered as one of the mechanisms, which leads to the resistance to third-generation tyrosine kinase inhibitors (TKI). Several reports have suggested that combination therapy with first- and third-generation TKI...

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Detalles Bibliográficos
Autores principales: Chen, Jianxin, Wang, Junhui, Wu, Xilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358086/
https://www.ncbi.nlm.nih.gov/pubmed/32753903
http://dx.doi.org/10.2147/OTT.S262594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358086/
https://www.ncbi.nlm.nih.gov/pubmed/32753903
http://dx.doi.org/10.2147/OTT.S262594

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