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The hypertensive effect of sorafenib is abolished by sildenafil

BACKGROUND: Contrasting to the well documented tyrosine kinase inhibitor (TKI)-induced hypertension, little is known on their intrinsic vasomotor effects. We investigated the vasomotor effects of sorafenib, a widely used multikinase inhibitor in the treatment of hepatocellular and renal cell carcino...

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Detalles Bibliográficos
Autores principales: Dabiré, Hubert, Dramé, Fatou, Cita, Nelly, Ghaleh, Bijan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358208/
https://www.ncbi.nlm.nih.gov/pubmed/32685197
http://dx.doi.org/10.1186/s40959-020-00064-w