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Dissecting the Functional Mechanisms of Somatic Copy-Number Alterations Based on Dysregulated ceRNA Networks across Cancers

Somatic copy-number alterations (SCNAs) drive tumor growth and evolution. However, the functional roles of SCNAs across the genome are still poorly understood. We provide an integrative strategy to characterize the functional roles of driver SCNAs in cancers based on dysregulated competing endogenou...

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Detalles Bibliográficos
Autores principales: Ping, Yanyan, Zhou, Yao, Hu, Jing, Pang, Lin, Xu, Chaohan, Xiao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358224/
https://www.ncbi.nlm.nih.gov/pubmed/32668393
http://dx.doi.org/10.1016/j.omtn.2020.06.012