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Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival

OBJECTIVES: Few reports have explored clinical biomarkers, including those identified by targeted exome sequencing (TES) of surgically resected small-cell lung cancer (SCLC) and correlation with patient survival. PATIENTS AND METHODS: We collected formalin-fixed paraffin-embedded tumor samples from...

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Detalles Bibliográficos
Autores principales: Yokouchi, Hiroshi, Nishihara, Hiroshi, Harada, Toshiyuki, Yamazaki, Shigeo, Kikuchi, Hajime, Oizumi, Satoshi, Uramoto, Hidetaka, Tanaka, Fumihiro, Harada, Masao, Akie, Kenji, Sugaya, Fumiko, Fujita, Yuka, Takamura, Kei, Kojima, Tetsuya, Higuchi, Mitsunori, Honjo, Osamu, Minami, Yoshinori, Watanabe, Naomi, Nishimura, Masaharu, Suzuki, Hiroyuki, Dosaka-Akita, Hirotoshi, Isobe, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358392/
https://www.ncbi.nlm.nih.gov/pubmed/32685741
http://dx.doi.org/10.1016/j.heliyon.2020.e04439