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Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival
OBJECTIVES: Few reports have explored clinical biomarkers, including those identified by targeted exome sequencing (TES) of surgically resected small-cell lung cancer (SCLC) and correlation with patient survival. PATIENTS AND METHODS: We collected formalin-fixed paraffin-embedded tumor samples from...
Autores principales: | Yokouchi, Hiroshi, Nishihara, Hiroshi, Harada, Toshiyuki, Yamazaki, Shigeo, Kikuchi, Hajime, Oizumi, Satoshi, Uramoto, Hidetaka, Tanaka, Fumihiro, Harada, Masao, Akie, Kenji, Sugaya, Fumiko, Fujita, Yuka, Takamura, Kei, Kojima, Tetsuya, Higuchi, Mitsunori, Honjo, Osamu, Minami, Yoshinori, Watanabe, Naomi, Nishimura, Masaharu, Suzuki, Hiroyuki, Dosaka-Akita, Hirotoshi, Isobe, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358392/ https://www.ncbi.nlm.nih.gov/pubmed/32685741 http://dx.doi.org/10.1016/j.heliyon.2020.e04439 |
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