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Arginine-Based Poly(I:C)-Loaded Nanocomplexes for the Polarization of Macrophages Toward M1-Antitumoral Effectors

Background: Tumor-associated macrophages (TAMs), with M2-like immunosuppressive profiles, are key players in the development and dissemination of tumors. Hence, the induction of M1 pro-inflammatory and anti-tumoral states is critical to fight against cancer cells. The activation of the endosomal tol...

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Detalles Bibliográficos
Autores principales: Dacoba, Tamara G., Anfray, Clément, Mainini, Francesco, Allavena, Paola, Alonso, María José, Torres Andón, Fernando, Crecente-Campo, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358452/
https://www.ncbi.nlm.nih.gov/pubmed/32733469
http://dx.doi.org/10.3389/fimmu.2020.01412