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Arginine-Based Poly(I:C)-Loaded Nanocomplexes for the Polarization of Macrophages Toward M1-Antitumoral Effectors
Background: Tumor-associated macrophages (TAMs), with M2-like immunosuppressive profiles, are key players in the development and dissemination of tumors. Hence, the induction of M1 pro-inflammatory and anti-tumoral states is critical to fight against cancer cells. The activation of the endosomal tol...
Autores principales: | Dacoba, Tamara G., Anfray, Clément, Mainini, Francesco, Allavena, Paola, Alonso, María José, Torres Andón, Fernando, Crecente-Campo, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358452/ https://www.ncbi.nlm.nih.gov/pubmed/32733469 http://dx.doi.org/10.3389/fimmu.2020.01412 |
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