Melatonin sensitises shikonin-induced cancer cell death mediated by oxidative stress via inhibition of the SIRT3/SOD2-AKT pathway

Recent research suggests that melatonin (Mel), an endogenous hormone and natural supplement, possesses anti-proliferative effects and can sensitise cells to anti-cancer therapies. Although shikonin (SHK) also possesses potential anti-cancer properties, the poor solubility and severe systemic toxicit...

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Detalles Bibliográficos
Autores principales: Li, Mengling, Wu, Chengai, Muhammad, Jibran Sualeh, Yan, Dan, Tsuneyama, Koichi, Hatta, Hideki, Cui, Zheng-Guo, Inadera, Hidekuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358455/
https://www.ncbi.nlm.nih.gov/pubmed/32863233
http://dx.doi.org/10.1016/j.redox.2020.101632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358455/
https://www.ncbi.nlm.nih.gov/pubmed/32863233
http://dx.doi.org/10.1016/j.redox.2020.101632

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