Betulinic Acid Protects From Bone Loss in Ovariectomized Mice and Suppresses RANKL-Associated Osteoclastogenesis by Inhibiting the MAPK and NFATc1 Pathways

Osteoclasts with elevated bone resorption are commonly present in postmenopausal osteoporosis, and other osteolytic pathologies. Therefore, suppressing osteoclast generation and function has been the main focus of osteoporosis treatment. Betulinic acid (BA) represents a triterpenoid mainly purified...

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Detalles Bibliográficos
Autores principales: Wei, Jiyong, Li, Yicheng, Liu, Qian, Lan, Yanni, Wei, Chengming, Tian, Kun, Wu, Liwei, Lin, Chunbo, Xu, Jiake, Zhao, Jinmin, Yang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358641/
https://www.ncbi.nlm.nih.gov/pubmed/32733253
http://dx.doi.org/10.3389/fphar.2020.01025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358641/
https://www.ncbi.nlm.nih.gov/pubmed/32733253
http://dx.doi.org/10.3389/fphar.2020.01025

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