Absence of Plekhg5 Results in Myelin Infoldings Corresponding to an Impaired Schwann Cell Autophagy, and a Reduced T-Cell Infiltration Into Peripheral Nerves

Inflammation and dysregulation of the immune system are hallmarks of several neurodegenerative diseases. An activated immune response is considered to be the cause of myelin breakdown in demyelinating disorders. In the peripheral nervous system (PNS), myelin can be degraded in an autophagy-dependent...

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Detalles Bibliográficos
Autores principales: Lüningschrör, Patrick, Slotta, Carsten, Heimann, Peter, Briese, Michael, Weikert, Ulrich M., Massih, Bita, Appenzeller, Silke, Sendtner, Michael, Kaltschmidt, Christian, Kaltschmidt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358705/
https://www.ncbi.nlm.nih.gov/pubmed/32733205
http://dx.doi.org/10.3389/fncel.2020.00185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358705/
https://www.ncbi.nlm.nih.gov/pubmed/32733205
http://dx.doi.org/10.3389/fncel.2020.00185

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