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Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons

Insulin signaling is an integral component of healthy brain function, with evidence of positive insulin-mediated alterations in synaptic integrity, cerebral blood flow, inflammation, and memory. However, the specific pathways targeted by this peptide remain unclear. Previously, our lab used a molecu...

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Detalles Bibliográficos
Autores principales: Frazier, Hilaree N., Ghoweri, Adam O., Anderson, Katie L., Lin, Ruei-Lung, Popa, Gabriel J., Mendenhall, Michael D., Reagan, Lawrence P., Craven, Rolf J., Thibault, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358706/
https://www.ncbi.nlm.nih.gov/pubmed/32733189
http://dx.doi.org/10.3389/fnins.2020.00668