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Elevating Insulin Signaling Using a Constitutively Active Insulin Receptor Increases Glucose Metabolism and Expression of GLUT3 in Hippocampal Neurons
Insulin signaling is an integral component of healthy brain function, with evidence of positive insulin-mediated alterations in synaptic integrity, cerebral blood flow, inflammation, and memory. However, the specific pathways targeted by this peptide remain unclear. Previously, our lab used a molecu...
Autores principales: | Frazier, Hilaree N., Ghoweri, Adam O., Anderson, Katie L., Lin, Ruei-Lung, Popa, Gabriel J., Mendenhall, Michael D., Reagan, Lawrence P., Craven, Rolf J., Thibault, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358706/ https://www.ncbi.nlm.nih.gov/pubmed/32733189 http://dx.doi.org/10.3389/fnins.2020.00668 |
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