Multilateral Bioinformatics Analyses Reveal the Function-Oriented Target Specificities and Recognition of the RNA-Binding Protein SFPQ

RNA-binding proteins (RBPs) recognize consensus sequences and regulate specific target mRNAs. However, large-scale CLIP-seq revealed loose and broad binding of RBPs to larger proportion of expressed mRNAs: e.g. SFPQ binds to >10,000 pre-mRNAs but distinctly regulates <200 target genes during n...

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Detalles Bibliográficos
Autores principales: Iida, Kei, Hagiwara, Masatoshi, Takeuchi, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358709/
https://www.ncbi.nlm.nih.gov/pubmed/32659723
http://dx.doi.org/10.1016/j.isci.2020.101325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358709/
https://www.ncbi.nlm.nih.gov/pubmed/32659723
http://dx.doi.org/10.1016/j.isci.2020.101325

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