Differential Expression of Ormdl Genes in the Islets of Mice and Humans with Obesity

The orosomucoid-like (Ormdl) proteins play a critical role in sphingolipid homeostasis, inflammation, and ER stress, all of which are associated with obesity and βcell dysfunction. However, their roles in β cells and obesity remain unknown. Here, we show that islets from overweight/obese human donor...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Hugo, Fenske, Rachel J., Akcan, Tugce, Domask, Elliot, Davis, Dawn B., Kimple, Michelle E., Engin, Feyza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358727/
https://www.ncbi.nlm.nih.gov/pubmed/32659722
http://dx.doi.org/10.1016/j.isci.2020.101324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358727/
https://www.ncbi.nlm.nih.gov/pubmed/32659722
http://dx.doi.org/10.1016/j.isci.2020.101324

Ejemplares similares